cell programming

Methods for reprogramming of mammalian somatic cells (mature mammalian somatic cells) into multi-potent precursor cells using protein delivering reagent from OZ Biosciences.

this patent describes the use of Pro-Deliverin to tranport protein into human dermal fibroblasts with 50 % transfection efficiency.

Pro-DeliverIN™ is an innovative reagent allowing intracellular delivery of biologically active proteins. This lipid-based formulation is the first serum compatible reagent to deliver functional proteins into living cells.

Patent reference: US 2012/0301965 A1

CELL PROGRAMMING

Abstract The present invention is concerned with methods for reprogramming of mammalian somatic cells and in particular to reprogramming of mature mammalian somatic cells into multi-potent precursor cells.

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Inventors:	Connor; Bronwen Jane; (North Shore City, NZ) ; Dottori; Mirella; (Victoria, AU) ; Maucksch; Christof; (Auckland, NZ)
Assignee:	THE UNIVERSITY OF MELBOURNE Victoria AU AUCKLAND UNISERVICES LIMITED Auckland NZ